Kinetic data for "CTX-M%"

Number of results: 164

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#	Protein Name	Antibiotic	kcat (s-1)	Km (µM)	kcat/KM
1	CTX-M-10	Cefuroxime		38
2	CTX-M-10	Cefotaxime		28
3	CTX-M-10	Penicillin G		34
4	CTX-M-10	Cephaloridine		96
5	CTX-M-117	Cefuroxime	81±10	6.2±1.2	13
6	CTX-M-117	Aztreonam	8.4±2	177±28	0.05
7	CTX-M-117	Cefotaxime	75±10	15±3	5
8	CTX-M-117	Cefepime	6.9±2	46±15	0.15
9	CTX-M-117	Penicillin G	29±4	202±30	0.14
10	CTX-M-117	Ceftazidime	2.6±0.5	75±8	0.03
11	CTX-M-117	Cephalothin	1590±190	118±27	13.5
12	CTX-M-16	Amoxicillin	40	10	4
13	CTX-M-16	Cefuroxime	500	45	11
14	CTX-M-16	Aztreonam	3	17	0.2
15	CTX-M-16	Cefotaxime	1400	150	9.3
16	CTX-M-16	Penicillin G	65	6	10.8
17	CTX-M-16	Ceftazidime	15	350	0.04
18	CTX-M-16	Cefpirome	840	520	1.6
19	CTX-M-16	Cephalothin	2800	83	33.7
20	CTX-M-16	Ticarcillin	10	13	0.8
21	CTX-M-16	Piperacillin	45	8	5.6
22	CTX-M-18	Aztreonam	2	286	0.01
23	CTX-M-18	Cefotaxime	20	54	0.04
24	CTX-M-18	Cefpirome	65	650	0.01
25	CTX-M-18	Cefepime	20	525	0.04
26	CTX-M-18	Benzylpenicillin	30	29	1
27	CTX-M-18	Cephaloridine	7	216	0
28	CTX-M-18	Ticarcillin	3	17	0.16
29	CTX-M-18	Ceftriaxone	20	20	0.09
30	CTX-M-18	Piperacillin	15	23	0.06
31	CTX-M-18	Amoxicillin	10	105	0.1
32	CTX-M-18	Cefuroxime	40	70	0.06
33	CTX-M-19	Ceftazidime	0.02	25	0
34	CTX-M-19	Benzylpenicillin	5	15	0.33
35	CTX-M-19	Cephaloridine	30	123	0.24
36	CTX-M-19	Ticarcillin	1	30	0.03
37	CTX-M-19	Ceftriaxone	0.1	80	0
38	CTX-M-19	Piperacillin	8	10	0.8
39	CTX-M-19	Amoxicillin	1	100	0.01
40	CTX-M-19	Cefuroxime	8	40	0.2
41	CTX-M-19	Cefotaxime	3	60	0.05
42	CTX-M-25	Ceftazidime	33	13	2.6
43	CTX-M-25	Benzylpenicillin	33	74	0.4
44	CTX-M-25	Ticarcillin	8.2	2.3	3.5
45	CTX-M-25	Cephalothin	230	190	1.2
46	CTX-M-25	Cefuroxime	190	44	4.3
47	CTX-M-25	Imipenem	<0.01
48	CTX-M-25	Cefoxitin	<0.01
49	CTX-M-25	Cefotaxime	101	28	3.6
50	CTX-M-25	Aztreonam	84	120	0.7
51	CTX-M-25	Ampicillin	5.9	7.7	0.8
52	CTX-M-27	Cefpirome	63	520	0.12
53	CTX-M-27	Ticarcillin	1	13	0.07
54	CTX-M-27	Cephalothin	232	83	2.8
55	CTX-M-27	Penicillin G	11	6	1.8
56	CTX-M-27	Piperacillin	9	8	1.1
57	CTX-M-27	Cefuroxime	79	45	1.75
58	CTX-M-27	Amoxicillin	5	10	0.5
59	CTX-M-27	Cefotaxime	113	150	0.75
60	CTX-M-27	Aztreonam	0.4	17	0.02
61	CTX-M-27	Ceftazidime	3	330	0.01
62	CTX-M-32	Cephalothin	928±16.4	211±0.5	4.4
63	CTX-M-32	Cefepime	43±8.8	1287±4.1	0.03
64	CTX-M-32	Cefuroxime	162±11.6	261±0.2	0.6
65	CTX-M-32	Cefotaxime	320±10.4	322±2.7	1
66	CTX-M-32	Aztreonam	1±0.4	31±0.7	0.03
67	CTX-M-32	Ceftazidime	0.91±0.5	271±0.2	0
68	CTX-M-32	Ampicillin	3±1.1	8±2.6	0.4
69	CTX-M-4	Penicillin G		22
70	CTX-M-4	Cefuroxime		210
71	CTX-M-4	Cefotaxime		295
72	CTX-M-4	Ampicillin		31
73	CTX-M-4	Cephalothin		103
74	CTX-M-53	Ticarcillin	10	18	0.5
75	CTX-M-53	Cefotaxime	585	180	3.2
76	CTX-M-53	Piperacillin	90	12	7.5
77	CTX-M-53	Aztreonam	4	14	0.3
78	CTX-M-53	Amoxicillin	85	40	2.1
79	CTX-M-53	Ceftazidime	14	174	0.1
80	CTX-M-53	Cephalothin	2000	122	16.4
81	CTX-M-53	Cefpirome	710	125	5.7
82	CTX-M-53	Penicillin G	135	10	13.5
83	CTX-M-53	Cefuroxime	292	80	3.6
84	CTX-M-54	Cefotaxime	34	182	0.2
85	CTX-M-54	Aztreonam	9	244	0.04
86	CTX-M-54	Cephaloridine	145	215	0.7
87	CTX-M-54	Ceftazidime	0.13	48	0
88	CTX-M-54	Ampicillin	4	33	0.1
89	CTX-M-54	Cephalothin	11	325	0.03
90	CTX-M-54	Cefuroxime	61	95	0.6
91	CTX-M-54	Nitrocefine	147	29	5.1
92	CTX-M-54	Benzylpenicillin	22	19	1.2
93	CTX-M-71	Cefepime	8.8±0.4	85±4	0.1
94	CTX-M-71	Meropenem	<0.07
95	CTX-M-71	Aztreonam	0.84±0.06	10±1	0.08
96	CTX-M-71	Cephaloridine	68±5	18±1	3.8
97	CTX-M-71	Piperacillin	27±0.5	3.2±0.2	8.4
98	CTX-M-71	Amoxicillin	49±0.5	5.2±0.9	9.4
99	CTX-M-71	Ceftazidime	0.69±0.1	180±11	0
100	CTX-M-71	Imipenem	<=0.07
101	CTX-M-71	Benzylpenicillin	58±0.6	4.9±0.2	11.8
102	CTX-M-71	Cefotaxime	65±2	130±0.7	0.5
103	CTX-M-72	Cephalothin	150.67±1.71	153.28±1.10	0.98
104	CTX-M-72	Cefuroxime	47±125	65.69±0.38	0.72
105	CTX-M-72	Cefotaxime	47.67±1.68	71.60±0.65	0.67
106	CTX-M-72	Penicillin G	22.33±1.10	18.89±1.76	1.18
107	CTX-M-72	Nitrocefine	21.33±1.21	16.47±0.91	1.3
108	CTX-M-72	Aztreonam	49.38±1.43	73.96±1.18	0.67
109	CTX-M-8	Amoxicillin		12
110	CTX-M-8	Ceftazidime		>500
111	CTX-M-8	Cephalothin		87
112	CTX-M-8	Imipenem		1
113	CTX-M-8	Cefuroxime		12
114	CTX-M-8	Cefotaxime		74
115	CTX-M-8	Cefoxitin		5
116	CTX-M-8	Benzylpenicillin		11
117	CTX-M-8	Cefpirome		1200
118	CTX-M-8	Aztreonam		800
119	CTX-M-8	Ticarcillin		14
120	CTX-M-8	Cefepime		990
121	CTX-M-8	Piperacillin		19
122	CTX-M-80	Cephalothin	189.6	160.72	1.18
123	CTX-M-80	Cefuroxime	50	52.27	0.96
124	CTX-M-80	Cefotaxime	47.2	49.34	0.96
125	CTX-M-80	Penicillin G	52.8	31.61	1.67
126	CTX-M-81	Cefuroxime	48.8	52.72	0.93
127	CTX-M-81	Cefotaxime	47.6	47.34	1.01
128	CTX-M-81	Penicillin G	54.4	31.86	1.71
129	CTX-M-81	Cephalothin	176.4	148.86	1.19
130	CTX-M-87	Ceftazidime	<0.01	300±48	<0.01
131	CTX-M-87	Cefuroxime	3500±120	443±26	7.9
132	CTX-M-87	Cefotaxime	1300±30	50±4.6	26
133	CTX-M-87	Penicillin G	1100±56	43±3.5	25.58
134	CTX-M-87	Aztreonam	<0.01	450±46	<0.01
135	CTX-M-87	Cefepime	<0.01	0.53±0.13	<0.02
136	CTX-M-87	Cephaloridine	1500±86	120±7.0	12.5
137	CTX-M-93	Penicillin G	0.07	22.5	0
138	CTX-M-93	Cephalothin	1.8	33	0.06
139	CTX-M-93	Cephaloridine	1.4	51	0.03
140	CTX-M-93	Ceftazidime	2.5	25.5	0.1
141	CTX-M-93	Cefuroxime	0.23	41.23	0.01
142	CTX-M-93	Cefotaxime	0.6	67	0.01

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